SCHEMBL21031904

SCHEMBL21031904

Cc1c(Cc2ccc3c(c2)C(F)C(F)(F)S3(=O)=O)c2cc(F)ccc2n1CC(=O)OCC(C)C

nearest known ligand 0.67

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 20/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21031902 0.87 PTGDR2 (0.87) PTGDR2
SCHEMBL21186598 0.71 PTGDR2 (0.61) PTGDR2
SCHEMBL21031900 0.71 PTGDR2 (0.59) PTGDR2
SCHEMBL2670064 0.69 PTGDR2 (0.62) PTGDR2
SCHEMBL21027850 0.69 PTGDR2 (0.52) PTGDR2
SCHEMBL21031856 0.68 PTGDR2 (0.73) PTGDR2
SCHEMBL21031954 0.68 PTGDR2 (0.64) PTGDR2
SCHEMBL21031956 0.67 PTGDR2 (0.69) PTGDR2
SCHEMBL2670041 0.67 PTGDR2 (0.64) PTGDR2
SCHEMBL1784755 0.66 PTGDR2 (0.72) PTGDR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3489233-B1 INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) 2022-01-12 EP disclosed
EP-3489233-A1 INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) 2019-05-29 EP disclosed