Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 15/20 | 0.65 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.46 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032217 | 0.89 | PTGDR2 (0.66) | PTGDR2AKR1B1 | |
| SCHEMBL21031903 | 0.87 | PTGDR2 (0.57) | PTGDR2AKR1A1AKR1B1 | |
| SCHEMBL21032466 | 0.87 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL21032709 | 0.87 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL21032511 | 0.87 | PTGDR2 (0.49) | PTGDR2AKR1A1AKR1B1 | |
| SCHEMBL21032593 | 0.85 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL21031858 | 0.84 | PTGDR2 (0.51) | PTGDR2 | |
| SCHEMBL24180035 | 0.83 | PTGDR2 (0.64) | PTGDR2AKR1B1 | |
| SCHEMBL21031848 | 0.81 | PTGDR2 (0.48) | PTGDR2 | |
| SCHEMBL21032195 | 0.79 | PTGDR2 (0.67) | PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |