Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.58 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.58 |
| ▸ | PTGIR | P43119 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21186600 | 0.83 | PTGDR2 (0.58) | PTGDR2 | |
| SCHEMBL24179998 | 0.81 | PTGDR2 (0.62) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 | |
| SCHEMBL21031852 | 0.81 | PTGDR2 (0.64) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 | |
| SCHEMBL21032176 | 0.79 | PTGDR2 (0.69) | PTGDR2PTGDRPTGIR | |
| SCHEMBL16210801 | 0.75 | PTGDR2 (0.54) | PTGDR2 | |
| SCHEMBL1786702 | 0.75 | PTGDR2 (0.85) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 | |
| SCHEMBL24180051 | 0.75 | PTGDR2 (0.52) | PTGDR2 | |
| Timapiprant SCHEMBL29648518 | 0.74 | PTGDR2 (1.00) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 | |
| Timapiprant SCHEMBL29379400 | 0.74 | PTGDR2 (1.00) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 | |
| Timapiprant SCHEMBL1782956 | 0.74 | PTGDR2 (1.00) | PTGDR2PTGDRPTGIRCYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |