Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.67 |
| ▸ | PTGIR | P43119 | 1/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032915 | 0.85 | PTGDR2 (0.73) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21032403 | 0.80 | PTGDR2 (1.00) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21032195 | 0.80 | PTGDR2 (0.67) | PTGDR2 | |
| SCHEMBL1783309 | 0.79 | PTGDR2 (0.71) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1784687 | 0.77 | PTGDR2 (0.68) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21032547 | 0.77 | PTGDR2 (1.00) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1784567 | 0.76 | PTGDR2 (0.67) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1786943 | 0.76 | PTGDR2 (0.67) | PTGDR2PTGIRPTGDR | |
| SCHEMBL4761775 | 0.76 | PTGDR2 (0.79) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1785769 | 0.75 | PTGDR2 (0.66) | PTGDR2PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |