Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 20/20 | 0.61 |
| ▸ | PTGIR | P43119 | 1/20 | 0.52 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24180008 | 0.84 | PTGDR2 (0.60) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21032216 | 0.82 | PTGDR2 (0.64) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21031860 | 0.81 | PTGDR2 (0.60) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21031853 | 0.78 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL4761775 | 0.78 | PTGDR2 (0.79) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1785678 | 0.77 | PTGDR2 (0.74) | PTGDR2 | |
| SCHEMBL1785782 | 0.77 | PTGDR2 (0.68) | PTGDR2PTGIRPTGDR | |
| SCHEMBL21031857 | 0.76 | PTGDR2 (0.64) | PTGDR2 | |
| SCHEMBL1782239 | 0.76 | PTGDR2 (1.00) | PTGDR2PTGIRPTGDR | |
| SCHEMBL1784434 | 0.76 | PTGDR2 (0.77) | PTGDR2PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489233-B1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO LTD (CN) | 2022-01-12 | — | — | EP | disclosed |
| EP-3489233-A1 | INDOLE DERIVATIVE USED AS CRTH2 INHIBITOR | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. (CN) | 2019-05-29 | — | — | EP | disclosed |