Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19847425 | 1.00 | TSHR (0.61) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL11900914 | 0.96 | TSHR (0.63) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL25993934 | 0.96 | TSHR (0.63) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL24028219 | 0.94 | TSHR (0.57) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL18556477 | 0.93 | TSHR (0.71) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL18123399 | 0.92 | TSHR (0.59) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL18123485 | 0.92 | TSHR (0.59) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL16802929 | 0.91 | TSHR (0.58) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL17658798 | 0.91 | TSHR (0.58) | TSHREPHX1ALDH1A1THRBTDP1 | |
| SCHEMBL18193272 | 0.91 | TSHR (0.58) | TSHREPHX1ALDH1A1THRBTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020234775-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION WITH PENDENT CYCLIC MOIETIES, METHODS, AND POLYMERIZABLE COMPOSITIONS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2020-11-26 | — | — | WO | disclosed |
| WO-2019104079-A1 | ORTHODONTIC ARTICLES COMPRISING POLYMERIZED COMPOSITION COMPRISING AT LEAST TWO FREE-RADICAL INITIATORS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |
| WO-2019104072-A1 | ORTHODONTIC ARTICLES COMPRISING CURED FREE-RADICALLY POLYMERIZABLE COMPOSITION COMPRISING POLYMER OR MACROMOLECULE WITH PHOTOINITIATOR GROUP | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2019-05-31 | — | — | WO | disclosed |