Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 4/20 | 0.40 |
| ▸ | MMP1 | P03956 | 4/20 | 0.40 |
| ▸ | MMP13 | P45452 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.37 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.37 |
| ▸ | RGS12 | O14924 | 1/20 | 0.37 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21035127 | 0.98 | ACACB (0.41) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035580 | 0.98 | ACACB (0.41) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035662 | 0.98 | ACACB (0.41) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21034927 | 0.94 | ACACB (0.42) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035086 | 0.94 | ACACB (0.42) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035006 | 0.94 | ACACB (0.42) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035644 | 0.94 | ACACB (0.42) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21036277 | 0.94 | ACACB (0.42) | ACACBKMT2AMEN1ADAM17MMP1 | |
| SCHEMBL21035536 | 0.92 | ACACB (0.41) | ACACBADAM17MMP1MMP13MMP9 | |
| SCHEMBL21035393 | 0.92 | ACACB (0.41) | ACACBADAM17MMP1MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104011-A1 | CERAMIDE GALACTOSYLTRANSFERASE INHIBITORS FOR THE TREATMENT OF DISEASE | BIOMARIN PHARMACEUTICAL INC. (US) | 2019-05-31 | — | — | WO | disclosed |