Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 19/20 | 0.65 |
| ▸ | MC3R | P41968 | 7/20 | 0.60 |
| ▸ | MC5R | P33032 | 6/20 | 0.60 |
| ▸ | MC1R | Q01726 | 6/20 | 0.60 |
| ▸ | PRCP | P42785 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19806322 | 0.99 | MC4R (0.67) | MC4RMC3RMC5RMC1RPRCP | |
| SCHEMBL21123794 | 0.91 | MC4R (0.57) | MC4RMC3RMC5RMC1R | |
| SCHEMBL20994302 | 0.90 | MC4R (0.58) | MC4RMC3RMC5RMC1R | |
| SCHEMBL20994297 | 0.90 | MC4R (0.58) | MC4RMC3RMC5RMC1R | |
| SCHEMBL21036763 | 0.90 | MC4R (0.67) | MC4RMC3RMC5RMC1RPRCP | |
| SCHEMBL23471480 | 0.89 | MC4R (0.68) | MC4RMC3RMC5RMC1RPRCP | |
| SCHEMBL21035888 | 0.88 | MC4R (0.66) | MC4RMC3RMC5RMC1RPRCP | |
| SCHEMBL21036744 | 0.86 | MC4R (0.58) | MC4RMC3RMC5RMC1R | |
| SCHEMBL21035850 | 0.84 | MC4R (0.67) | MC4RMC3RMC5RMC1RPRCP | |
| SCHEMBL21036522 | 0.83 | MC4R (0.69) | MC4RMC3RMC5RMC1RPRCP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489231-B1 | PIPERAZINE DERIVATIVE | ASTELLAS PHARMA INC (JP) | 2021-06-09 | — | — | EP | disclosed |
| EP-3489231-A1 | PIPERAZINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2019-05-29 | — | — | EP | disclosed |