Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | FABP3 | P05413 | 1/20 | 0.35 |
| ▸ | FABP4 | P15090 | 1/20 | 0.35 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1106863 | 0.80 | POLB (0.53) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL5001806 | 0.78 | KDM4E (0.52) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL18534720 | 0.78 | POLB (0.52) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL10343050 | 0.78 | KDM4E (0.52) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL29345253 | 0.78 | POLB (0.47) | KDM4EPOLBATMALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL8378279 | 0.77 | KDM4E (0.50) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL2495680 | 0.77 | POLB (0.59) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL17454835 | 0.75 | CYP1A2 (0.53) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL1896087 | 0.74 | KDM4E (0.62) | KDM4EPOLBATMALDH1A1MAPT | |
| SCHEMBL12327435 | 0.74 | POLB (0.52) | KDM4EPOLBATMALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3107902-B1 | COMPOUNDS AND METHODS FOR INHIBITING FASCIN | CORNELL UNIV CORNELL CENTER FOR TECHNOLOGY ENTERPRISE & COMMERCIALIZATION CCTEC (US) | 2021-04-07 | — | — | EP | disclosed |
| WO-2019104067-A1 | CO-THERAPIES INCLUDING A METASTASIS INHIBITOR | CORNELL UNIVERSITY (US) | 2019-05-31 | — | — | WO | disclosed |