Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12661555 | 1.00 | TP53 (0.39) | TP53KDM4EMEN1GLACYP2C19 | |
| SCHEMBL27277772 | 0.83 | TP53 (0.35) | TP53KDM4E | |
| SCHEMBL25855850 | 0.80 | ANPEP (0.37) | — | |
| SCHEMBL439571 | 0.79 | — | — | |
| SCHEMBL24218298 | 0.78 | TP53 (0.35) | TP53KDM4E | |
| SCHEMBL21864389 | 0.78 | ANPEP (0.39) | — | |
| SCHEMBL15343475 | 0.78 | — | — | |
| SCHEMBL20021196 | 0.78 | TP53 (0.35) | TP53KDM4E | |
| SCHEMBL21965251 | 0.76 | KDM4E (0.33) | TP53KDM4E | |
| SCHEMBL2270056 | 0.76 | KDM4E (0.33) | TP53KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489362-A1 | BIPARTITE AND TRIPARTITE SIGNALING IMMUNE CELLS | Baylor College of Medicine (US) | 2019-05-29 | — | — | EP | disclosed |