Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.67 |
| ▸ | TP53 | P04637 | 2/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 3/20 | 0.67 |
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA9 | Q16790 | 3/20 | 0.67 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21032748 | 0.89 | HTT (0.69) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21032749 | 0.89 | RXFP1 (0.69) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21033053 | 0.87 | RXFP1 (0.81) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21033051 | 0.87 | CA12 (0.65) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21032939 | 0.86 | CA12 (0.68) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21032750 | 0.86 | CA12 (0.64) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21032751 | 0.84 | CA12 (0.65) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21033392 | 0.84 | CA12 (0.68) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21032936 | 0.83 | CA12 (0.64) | RXFP1TP53CA12CA1CA2 | |
| SCHEMBL21033647 | 0.83 | CA12 (0.67) | RXFP1TP53CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2019104199-A1 | SMALL MOLECULE AGONISTS AND ANTAGONISTS OF NR2F6 ACTIVITY | REGEN BIOPHARMA INC. (US) | 2019-05-31 | — | — | WO | disclosed |