Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 19/20 | 0.57 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16593386 | 0.90 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL16593391 | 0.90 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL18027680 | 0.90 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL16593394 | 0.90 | CHRM1 (0.68) | CHRM1 | |
| SCHEMBL16593287 | 0.82 | CHRM1 (0.57) | CHRM1 | |
| SCHEMBL16593231 | 0.79 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL16593234 | 0.79 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL18027676 | 0.79 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL16593229 | 0.79 | CHRM1 (0.74) | CHRM1 | |
| SCHEMBL21043274 | 0.78 | CHRM1 (0.66) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3489237-A1 | 4-AZAINDOLE DERIVATIVES | Eisai R&D Management Co., Ltd. (JP) | 2019-05-29 | — | — | EP | disclosed |