Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTOR | P42345 | 6/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.39 |
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | LIPE | Q05469 | 1/20 | 0.38 |
| ▸ | WDR5 | P61964 | 3/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18848898 | 1.00 | MTOR (0.43) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15539839 | 0.95 | PIK3CA (0.45) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15538347 | 0.95 | PIK3CA (0.45) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15538344 | 0.95 | PIK3CA (0.45) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL18849079 | 0.94 | MTOR (0.43) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15539820 | 0.92 | MTOR (0.43) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15539265 | 0.92 | MTOR (0.43) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL15539262 | 0.92 | MTOR (0.43) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL18849015 | 0.91 | MTOR (0.42) | MTORPIK3CAALOX5APFEN1HCRTR1 | |
| SCHEMBL21043182 | 0.91 | MTOR (0.42) | MTORPIK3CAALOX5APFEN1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3074384-B1 | AMIDE DERIVATIVES FOR GPR119 AGONIST | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2019-05-22 | — | — | EP | disclosed |