⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3173111 | 0.75 | — | — | |
| SCHEMBL161777 | 0.75 | — | — | |
| SCHEMBL3611345 | 0.75 | — | — | |
| SCHEMBL27658120 | 0.71 | — | — | |
| SCHEMBL27852022 | 0.71 | — | — | |
| SCHEMBL6653553 | 0.71 | — | — | |
| SCHEMBL28811824 | 0.71 | — | — | |
| SCHEMBL27816917 | 0.67 | — | — | |
| SCHEMBL1192854 | 0.66 | MAPT (0.58) | — | |
| SCHEMBL272714 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117247393-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-12-19 | — | — | CN | disclosed |
| CN-117105890-A | Amide derivative, preparation method thereof and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116635373-A | Amide derivatives and use thereof | 成都百裕制药股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116635374-A | Amide derivatives and use thereof | 成都百裕制药股份有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-114716377-A | Process for producing pyrazole-amide compound | 日本烟草产业株式会社 | 2022-07-08 | — | — | CN | disclosed |
| CN-109476609-B | Process for producing pyrazole-amide compound | 日本烟草产业株式会社 | 2022-06-14 | — | — | CN | disclosed |
| CN-112851607-A | Amide derivative, preparation method and medical application thereof | 成都百裕制药股份有限公司 | 2021-05-28 | — | — | CN | disclosed |
| EP-3492452-A1 | PRODUCTION METHOD FOR PYRAZOLE-AMIDE COMPOUND | Japan Tobacco, Inc. (JP) | 2019-06-05 | — | — | EP | disclosed |
| CN-102459188-A | Novel 6-arylamino pyridone sulfonamides and 6-arylamino pyrazinone sulfonamdies as mek inhibitors | CHEMIZON BEIJING LTD | 2012-05-16 | — | — | CN | disclosed |