Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17822548 | 1.00 | TLR7 (1.00) | TLR7 | |
| SCHEMBL18087833 | 1.00 | TLR7 (1.00) | TLR7 | |
| SCHEMBL19763037 | 0.91 | TLR7 (0.84) | TLR7 | |
| SCHEMBL19763033 | 0.90 | TLR7 (0.82) | TLR7 | |
| SCHEMBL17822514 | 0.90 | TLR7 (0.81) | TLR7 | |
| SCHEMBL17822592 | 0.90 | TLR7 (0.81) | TLR7 | |
| SCHEMBL22281792 | 0.88 | TLR7 (0.79) | TLR7 | |
| SCHEMBL21046074 | 0.87 | TLR7 (0.76) | TLR7 | |
| SCHEMBL17822604 | 0.87 | TLR7 (0.79) | TLR7 | |
| SCHEMBL21046077 | 0.87 | TLR7 (0.79) | TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10618929-B2 | 3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection | HOFFMANN-LA ROCHE INC. (US) | 2020-04-14 | — | — | US | claimed |
| US-20190169222-A1 | NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2, 7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2019-06-06 | — | — | US | claimed |
| US-20190169222-A1 | NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2, 7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | HOFFMANN-LA ROCHE INC. (US) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190169222-A1 | NOVEL 3-SUBSTITUTED 5-AMINO-6H-THIAZOLO[4,5-D]PYRIMIDINE-2, 7-DIONE COMPOUNDS FOR THE TREATMENT AND PROPHYLAXIS OF VIRUS INFECTION | TYMP, ZC3HAV1, TPMT | TLR7 34/4885 |
| US-10618929-B2 | 3-substituted 5-amino-6H-thiazolo[4,5-D]pyrimidine-2, 7-dione compounds for the treatment and prophylaxis of virus infection | TPMT, DPYD, TYMP | TLR7 37/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.