Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 3/20 | 0.35 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.33 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.33 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.33 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 2/20 | 0.32 |
| ▸ | RARA | P10276 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | TDP2 | O95551 | 1/20 | 0.31 |
| ▸ | NSD2 | O96028 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22129964 | 0.92 | MCL1 (0.37) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| Phosphine SCHEMBL7063996 | 0.92 | MCL1 (0.37) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL27940198 | 0.90 | MCL1 (0.36) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| Phosphonic Acid SCHEMBL27941919 | 0.88 | MCL1 (0.35) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| Phosphonic Acid SCHEMBL28230146 | 0.86 | MCL1 (0.34) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL28465134 | 0.85 | NPC1 (0.33) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL27845228 | 0.82 | KDM4E (0.35) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL27945929 | 0.80 | HDAC7 (0.36) | MCL1SMN1; SMN2 | |
| Ethyl Hydrogen Phosphonate SCHEMBL27562760 | 0.79 | NPC1 (0.33) | MCL1AKR1C3AKR1C2AKR1B10AKR1C4 | |
| SCHEMBL28797066 | 0.79 | MEN1 (0.44) | AKR1C3AKR1C2AKR1B10AKR1C1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3206753-B1 | LATEX NAIL COMPOSITIONS HAVING LOW AMOUNTS OF PHOTO-INITIATOR | OREAL (FR) | 2019-06-12 | — | — | EP | claimed |