Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 17/20 | 0.70 |
| ▸ | MAOB | P27338 | 10/20 | 0.49 |
| ▸ | MAOA | P21397 | 9/20 | 0.49 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18183004 | 1.00 | KDM1A (0.70) | KDM1AMAOBMAOAKDM1BNFE2L2 | |
| Hydrochloric Acid SCHEMBL18172517 | 0.99 | KDM1A (0.68) | KDM1AMAOBMAOAKDM1BNFE2L2 | |
| Hydrochloric Acid SCHEMBL18172519 | 0.99 | KDM1A (0.68) | KDM1AMAOBMAOAKDM1BNFE2L2 | |
| SCHEMBL18172751 | 0.82 | KDM1A (1.00) | KDM1AMAOBMAOAKDM1B | |
| SCHEMBL18172754 | 0.82 | KDM1A (1.00) | KDM1AMAOBMAOAKDM1B | |
| SCHEMBL18181913 | 0.82 | KDM1A (1.00) | KDM1AMAOBMAOAKDM1B | |
| Hydrochloric Acid SCHEMBL18172587 | 0.81 | KDM1A (0.97) | KDM1AMAOBMAOAKDM1B | |
| Hydrochloric Acid SCHEMBL18172584 | 0.81 | KDM1A (0.97) | KDM1AMAOBMAOAKDM1B | |
| SCHEMBL18172552 | 0.80 | KDM1A (0.47) | KDM1AMAOBMAOA | |
| SCHEMBL18172555 | 0.80 | KDM1A (0.47) | KDM1AMAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3286172-B1 | LSD1 INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2019-06-12 | — | — | EP | disclosed |