Known targets — ChEMBL curated mechanism
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The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PAM | P19021 | 2/20 | 0.37 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL93600 | 0.96 | — | — | |
| Ethylene SCHEMBL624958 | 0.94 | TSHR (0.53) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL11791452 | 0.92 | TSHR (0.61) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL5922618 | 0.92 | TSHR (0.52) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL28138984 | 0.90 | TSHR (0.50) | TSHRCES2CES1DGKAMAPT | |
| Vinyl Chloride SCHEMBL8507026 | 0.90 | TSHR (0.50) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL35593 | 0.89 | TSHR (0.63) | TSHRCES2CES1DGKAMAPT | |
| Ethylene SCHEMBL624446 | 0.88 | TSHR (0.61) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL953501 | 0.88 | TSHR (0.67) | TSHRCES2CES1DGKAMAPT | |
| SCHEMBL680310 | 0.88 | TSHR (0.67) | TSHRCES2CES1DGKAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10953142-B2 | Biological component adhesion-suppressing material | TORAY INDUSTRIES, INC. (JP) | 2021-03-23 | — | — | US | disclosed |
| US-20200215239-A1 | BIOLOGICAL COMPONENT ADHESION-SUPPRESSING MATERIAL | TORAY INDUSTRIES, INC. (JP) | 2020-07-09 | — | — | US | disclosed |
| EP-3495004-A1 | BIOLOGICAL COMPONENT ADHESION-SUPPRESSING MATERIAL | Toray Industries, Inc. (JP) | 2019-06-12 | — | — | EP | disclosed |