Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 1.00 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.63 |
| ▸ | BRD2 | P25440 | 1/20 | 0.49 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.49 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19934746 | 1.00 | BRD4 (1.00) | BRD4BAZ2ABRD2EP300BRD3 | |
| SCHEMBL21049983 | 1.00 | BRD4 (1.00) | BRD4BAZ2ABRD2EP300BRD3 | |
| SCHEMBL19924674 | 0.90 | BRD4 (0.81) | BRD4BAZ2A | |
| SCHEMBL19924647 | 0.87 | BRD4 (0.77) | BRD4BAZ2A | |
| SCHEMBL21049981 | 0.83 | BRD4 (0.71) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL19934833 | 0.83 | BRD4 (0.71) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL21049972 | 0.83 | BRD4 (0.71) | BRD4BRD2EP300BRD3BRDT | |
| SCHEMBL21049988 | 0.78 | BRD4 (1.00) | BRD4BAZ2A | |
| SCHEMBL19934767 | 0.78 | BRD4 (1.00) | BRD4BAZ2A | |
| SCHEMBL21049982 | 0.78 | BRD4 (1.00) | BRD4BAZ2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190175571-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2019-06-13 | — | — | US | claimed |
| US-20190175571-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED (GB) | 2019-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190175571-A1 | IMIDAZOLE DERIVATIVES AND THEIR USE IN THE TREATMENT OF AUTOIMMUNE OR INFLAMMATORY DISEASES OR CANCERS | BRD4, BRPF3, BRD3 | BRD4 1/4885BAZ2A 16/4885BRD2 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.