Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 20/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 20/20 | 0.53 |
| ▸ | CHRM2 | P08172 | 12/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 14/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22468162 | 0.90 | CHRM1 (0.43) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468163 | 0.90 | CHRM1 (0.43) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468122 | 0.87 | HCRTR1 (0.41) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468125 | 0.87 | HCRTR1 (0.41) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL17259802 | 0.86 | CHRM1 (0.44) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL17259804 | 0.86 | CHRM1 (0.44) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468132 | 0.86 | CHRM3 (0.54) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468135 | 0.86 | CHRM1 (0.40) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468137 | 0.86 | CHRM1 (0.40) | CHRM1CHRM3CHRM2CHRM5 | |
| SCHEMBL22468133 | 0.86 | CHRM3 (0.54) | CHRM1CHRM3CHRM2CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3720852-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2020-10-14 | — | — | EP | disclosed |
| WO-2019110521-A1 | FLUOROPHENYL SUBSTITUTED MUSCARINIC RECEPTOR LIGANDS WITH SELECTIVITY FOR M3 OVER M2 | Friedrich-Alexander-Universität Erlangen-Nürnberg (DE) | 2019-06-13 | — | — | WO | disclosed |