Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIKFYVE | Q9Y2I7 | 10/20 | 0.62 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | FES | P07332 | 1/20 | 0.38 |
| ▸ | FER | P16591 | 1/20 | 0.38 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
| ▸ | FRK | P42685 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CAMK1D | Q8IU85 | 1/20 | 0.38 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30312463 | 1.00 | PIKFYVE (0.62) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL30312442 | 0.99 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21054236 | 0.99 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21054505 | 0.98 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL30312534 | 0.98 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21054117 | 0.95 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL30312384 | 0.93 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21055036 | 0.93 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL21055045 | 0.93 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD | |
| SCHEMBL30312359 | 0.93 | PIKFYVE (0.63) | PIKFYVELMNAMAPTKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11603372-B2 | Compounds and therapeutic uses thereof | VIOGEN BIOSCIENCES, LLC (US) | 2023-03-14 | — | — | US | claimed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | claimed |
| WO-2019113523-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | BAJJI ASHOK (US) | 2019-06-13 | — | — | WO | claimed |
| US-20240016810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. | 2024-01-18 | — | — | US | disclosed |
| US-11603372-B2 | Compounds and therapeutic uses thereof | VIOGEN BIOSCIENCES, LLC (US) | 2023-03-14 | — | — | US | disclosed |
| WO-2021252895-A2 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | YUMANITY THERAPEUTICS, INC. (US) | 2021-12-16 | — | — | WO | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | VIOGEN BIOSCIENCES, LLC | 2021-04-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240016810-A1 | COMPOSITIONS AND METHODS FOR THE TREATMENT AND PREVENTION OF NEUROLOGICAL DISORDERS | TARDBP, PIKFYVE, FUS | PIKFYVE 2/4885LMNA 2725/4885MAPT 33/4885 |
| US-11603372-B2 | Compounds and therapeutic uses thereof | IL15, IL17A, IL2 | PIKFYVE 944/4885LMNA 1857/4885MAPT 2341/4885 |
| US-20210122752-A1 | COMPOUNDS AND THERAPEUTIC USES THEREOF | IL15, IL17A, IL2 | PIKFYVE 944/4885LMNA 1857/4885MAPT 2341/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.