SCHEMBL21055932

SCHEMBL21055932

O=C(O)CCCCCCCCCCC(=O)NC(CCC(=O)NC(CCC(=O)NCCOCCOCC(=O)NCCOCCOCC(=O)NC(CCCCNC(=O)CBr)C(=O)O)C(=O)O)C(=O)O

nearest known ligand 0.69

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.69
▸ FOLH1 Q04609 3/20 0.46
▸ CCKAR P32238 5/20 0.43
▸ CCKBR P32239 5/20 0.43
▸ NOD1 Q9Y239 2/20 0.42
▸ GLO1 Q04760 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17884371 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL12685763 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL19513174 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL19513172 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL19022113 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL19028012 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL19022117 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL17884363 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL21096841 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1
SCHEMBL17884370 1.00 GLP1R (0.69) GLP1RFOLH1CCKARCCKBRNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3236991-B1 FGF21 DERIVATIVES AND USES THEREOF NOVO NORDISK AS (DK) 2019-06-19 — — EP disclosed
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