Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 7/20 | 0.61 |
| ▸ | PPARG | P37231 | 6/20 | 0.59 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.57 |
| ▸ | GPR27 | Q9NS67 | 1/20 | 0.57 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.53 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.53 |
| ▸ | ACLY | P53396 | 1/20 | 0.53 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21056023 | 0.90 | PPARG (0.60) | SMOPPARGAVPR2GPR27TAS1R3 | |
| SCHEMBL21056018 | 0.85 | PPARG (0.82) | SMOPPARGAVPR2GPR27 | |
| SCHEMBL21056013 | 0.84 | GRM5 (0.61) | SMOAVPR2GPR27ACLYTMPRSS4 | |
| SCHEMBL30436926 | 0.82 | PPARG (0.82) | SMOPPARGHTT | |
| SCHEMBL21055970 | 0.82 | PPARG (0.82) | SMOPPARGHTT | |
| SCHEMBL21105529 | 0.80 | SMO (0.66) | SMOPPARGKDM4EMEN1LMNA | |
| SCHEMBL18160421 | 0.78 | TMPRSS4 (0.58) | PPARGAVPR2GPR27TAS1R3TAS1R1 | |
| SCHEMBL18145983 | 0.78 | TMPRSS4 (0.58) | PPARGAVPR2GPR27TAS1R3TAS1R1 | |
| SCHEMBL30435685 | 0.78 | PPARG (0.71) | SMOPPARGMEN1KMT2AHTT | |
| SCHEMBL25349163 | 0.78 | TMPRSS4 (0.72) | PPARGTAS1R3TAS1R1TAS1R2TMPRSS4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3498694-A1 | NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2019-06-19 | — | — | EP | claimed |
| EP-3498694-A1 | NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2019-06-19 | — | — | EP | disclosed |
| EP-3498694-A1 | NEW BENZAMIDE DERIVATIVES AS PPAR-GAMMA MODULATORS | MEDIBIOFARMA, S.L. (ES) | 2019-06-19 | — | — | EP | disclosed |