⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5084611 | 1.00 | — | — | |
| SCHEMBL3551986 | 0.97 | — | — | |
| SCHEMBL418046 | 0.97 | — | — | |
| SCHEMBL3542055 | 0.97 | — | — | |
| SCHEMBL3543735 | 0.97 | — | — | |
| SCHEMBL183673 | 0.97 | — | — | |
| SCHEMBL3544133 | 0.97 | — | — | |
| Methane SCHEMBL18695290 | 0.94 | — | — | |
| SCHEMBL15365152 | 0.89 | — | — | |
| SCHEMBL1155 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4399216-A1 | IMMUNOMODULATING AZALIDES | Zoetis Services LLC (US) | 2024-07-17 | — | — | EP | claimed |
| EP-3652180-B1 | SUBSTITUTED BENZOXAZOLE AND BENZOFURAN COMPOUNDS AS PDE7 INHIBITORS | DART NEUROSCIENCE LLC (US) | 2023-11-29 | — | — | EP | claimed |
| CN-116874659-A | Low-temperature secondary photo-curing grafting oligomer and photosensitive resin composition containing same | 深圳市安云鑫新材料科技有限公司 | 2023-10-13 | — | — | CN | claimed |
| US-20230322976-A1 | METHOD OF EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD OF PRODUCING COMPOSITE BODY | BIODYNAMIC RESEARCH FOUNDATION (JP) | 2023-10-12 | — | — | US | claimed |
| EP-4190824-A1 | METHOD FOR EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD FOR PRODUCING COMPOSITE BODY | Toray Industries, Inc. (JP) | 2023-06-07 | — | — | EP | claimed |
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | claimed |
| WO-2023038852-A1 | IMMUNOMODULATING AZALIDES | ZOETIS SERVICES LLC (US) | 2023-03-16 | — | — | WO | claimed |
| EP-4118091-A1 | IMMUNOMODULATING UREA AZALIDES | Zoetis Services LLC (US) | 2023-01-18 | — | — | EP | claimed |
| CN-115552235-A | Method for evaluating purity of drug contained in complex and method for producing complex | 东丽株式会社 | 2022-12-30 | — | — | CN | claimed |
| WO-2021183759-A1 | IMMUNOMODULATING IMINE-OXAZOLINE AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | claimed |
| WO-2021183758-A1 | IMMUNOMODULATING UREA AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | claimed |
| WO-2021183754-A1 | IMMUNOMODULATING TRIFLUOROMETHYL-AMINAL AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | claimed |
| CN-108884070-B | Pyridyl derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2021-07-02 | — | — | CN | claimed |
| EP-3418275-B1 | NOVEL 2,3,5-SUBSTITUTED THIOPHENE COMPOUND AS PROTEIN KINASE INHIBITOR | KOREA INST SCI & TECH (KR) | 2021-03-17 | — | — | EP | claimed |
| EP-3191467-B1 | COMPOUNDS AND COMPOSITIONS AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2020-10-21 | — | — | EP | claimed |
| WO-2020081840-A1 | METHODS OF TREATING CANCER WITH ARYL HYDROCARBON RECEPTOR ANTAGONISTS | Magenta Therapeutics Inc. (US) | 2020-04-23 | — | — | WO | claimed |
| CN-110770214-A | Heterocyclic P2X7 antagonists | 阿克萨姆股份公司 | 2020-02-07 | — | — | CN | claimed |
| CN-110730778-A | Photochromic indeno-fused phenanthropyran compounds | 光学转变有限公司 | 2020-01-24 | — | — | CN | claimed |
| WO-2019233440-A1 | COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES | 江苏新元素医药科技有限公司 (CN) | 2019-12-12 | — | — | WO | claimed |
| CN-118201918-A | DDR1 and DDR2 inhibitors for the treatment of cancer and fibrotic diseases | 莱德克斯制药公共有限公司 | 2024-06-14 | — | — | CN | disclosed |
| CN-117794992-A | Process for modifying aqueous polymer latex | 巴斯夫欧洲公司 | 2024-03-29 | — | — | CN | disclosed |
| CN-117736222-A | MTA synergistic PRMT5 inhibitor compounds having tricyclic or tetracyclic ring structures | 烨辉医药科技(上海)有限公司 | 2024-03-22 | — | — | CN | disclosed |
| WO-2024051696-A1 | COMPOUND FOR RNA CAPPING AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2024-03-14 | — | — | WO | disclosed |
| WO-2024012565-A1 | MEMANTINE DERIVATIVE, PHARMACEUTICAL COMPOSITION THEREOF AND USE THEREOF | 广州市恒诺康医药科技有限公司 | 2024-01-18 | — | — | WO | disclosed |
| CN-111655681-B | Heterocyclylamino-substituted triazoles as modulators of Rho-related protein kinases | 莱德克斯制药公共有限公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-4294392-A1 | TARGETED BIFUNCTIONAL DEGRADERS AND METHODS USING SAME | Yale University, Inc. (US) | 2023-12-27 | — | — | EP | disclosed |
| CN-117136203-A | Aqueous polymer dispersions of hollow polymer particles | 巴斯夫欧洲公司 | 2023-11-28 | — | — | CN | disclosed |
| WO-2023207960-A1 | FUSED PYRIMIDINE-BASED DERIVATIVE, METHOD FOR PREPARING SAME, AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116874659-A | Low-temperature secondary photo-curing grafting oligomer and photosensitive resin composition containing same | 深圳市安云鑫新材料科技有限公司 | 2023-10-13 | — | — | CN | disclosed |
| US-20230322976-A1 | METHOD OF EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD OF PRODUCING COMPOSITE BODY | BIODYNAMIC RESEARCH FOUNDATION (JP) | 2023-10-12 | — | — | US | disclosed |
| CN-116635032-A | Compounds and methods for treating ocular disorders | 阿祖拉眼科有限公司 | 2023-08-22 | — | — | CN | disclosed |
| CN-116615417-A | 1, 4-diheterocycle substituted aromatic ring or aromatic heterocyclic compound and application thereof | 广州必贝特医药股份有限公司 | 2023-08-18 | — | — | CN | disclosed |
| CN-116568677-A | piperidin-1-yl-N-pyridin-3-yl-2-oxoacetamide derivatives useful for the treatment of MTAP deficiency and/or MTA accumulating cancers | 探戈医药股份有限公司 | 2023-08-08 | — | — | CN | disclosed |
| EP-4190824-A1 | METHOD FOR EVALUATING DEGREE OF PURITY OF PHARMACEUTICAL SUBSTANCE CONTAINED IN COMPOSITE BODY, AND METHOD FOR PRODUCING COMPOSITE BODY | Toray Industries, Inc. (JP) | 2023-06-07 | — | — | EP | disclosed |
| CN-116194109-A | Combination of antibody-drug conjugate and ATM inhibitor | 阿斯利康(英国)有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-116157388-A | Carbocyclic amide derivative and application thereof in medicine | 四川海思科制药有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115996932-A | New macrocyclic LRRK2 kinase inhibitors | 法国施维雅药厂 | 2023-04-21 | — | — | CN | disclosed |
| CN-115698009-A | CD73 inhibiting 2,4-dioxopyrimidine compounds | 吉利德科学公司 | 2023-02-03 | — | — | CN | disclosed |
| EP-4118092-A1 | IMMUNOMODULATING O-HET-ARYL AZALIDES | Zoetis Services LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| EP-4118091-A1 | IMMUNOMODULATING UREA AZALIDES | Zoetis Services LLC (US) | 2023-01-18 | — | — | EP | disclosed |
| CN-115552235-A | Method for evaluating purity of drug contained in complex and method for producing complex | 东丽株式会社 | 2022-12-30 | — | — | CN | disclosed |
| CN-109152771-B | Use of 2-substituted indazoles for the treatment and prevention of autoimmune diseases | 拜耳医药股份有限公司 | 2022-07-19 | — | — | CN | disclosed |
| CN-110305109-B | Novel substituted indazoles, method for the production thereof, pharmaceutical preparations containing same, and use thereof for producing medicaments | 拜耳医药股份有限公司 | 2022-04-08 | — | — | CN | disclosed |
| CN-113490667-A | Imidazopyridine derivatives as dual FGFR and VEGFR inhibitors | 南京明德新药研发有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-113423427-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2021-09-21 | — | — | CN | disclosed |
| WO-2021183759-A1 | IMMUNOMODULATING IMINE-OXAZOLINE AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021183758-A1 | IMMUNOMODULATING UREA AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021183754-A1 | IMMUNOMODULATING TRIFLUOROMETHYL-AMINAL AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| WO-2021183762-A1 | IMMUNOMODULATING O-HET-ARYL AZALIDES | ZOETIS SERVICES LLC (US) | 2021-09-16 | — | — | WO | disclosed |
| EP-3873938-A1 | DC-SIGN ANTIBODY CONJUGATES COMPRISING STING AGONISTS | Novartis AG (CH) | 2021-09-08 | — | — | EP | disclosed |
| EP-3874027-A2 | METHODS FOR HEMATOPOIETIC STEM AND PROGENITOR CELL TRANSPLANT THERAPY | Magenta Therapeutics, Inc. (US) | 2021-09-08 | — | — | EP | disclosed |
| WO-2021153213-A1 | MOLDED BODY, PRECURSOR THEREOF, METHODS FOR PRODUCING SAME, AND USES THEREOF | 株式会社ダイセル | 2021-08-05 | — | — | WO | disclosed |
| CN-108137541-B | Pyridone dicarboxamides for use as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2021-07-06 | — | — | CN | disclosed |
| CN-108884070-B | Pyridyl derivatives as bromodomain inhibitors | 葛兰素史克知识产权第二有限公司 | 2021-07-02 | — | — | CN | disclosed |
| CN-107879960-B | Lipids and lipid compositions for delivery of active ingredients | 诺华股份有限公司 | 2021-06-22 | — | — | CN | disclosed |
| EP-3820567-A1 | SPIROCYCLIC INDANE ANALOGUES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2021-05-19 | — | — | EP | disclosed |
| CN-107660204-B | Method for producing indazole derivative | 葛兰素史克知识产权开发有限公司 | 2021-04-13 | — | — | CN | disclosed |
| EP-3768301-A1 | COMPOSITIONS AND METHODS OF FAS INHIBITION | Onl Therapeutics, Inc. (US) | 2021-01-27 | — | — | EP | disclosed |
| CN-112105385-A | IRAK degrading agents and uses thereof | 凯麦拉医疗公司 | 2020-12-18 | — | — | CN | disclosed |
| CN-110526955-B | 18 beta-glycyrrhetinic acid compound containing hydroxamic acid structural fragment and application thereof | 沈阳药科大学 | 2020-12-18 | — | — | CN | disclosed |
| CN-112074519-A | N- [ 4-oxo-2, 3-dihydro-1, 5-benzoxazepin-3-yl ] -5, 6-dihydro-4H-pyrrolo [1,2-B ] pyrazole-2-carboxamide derivatives and related compounds as RIP1 kinase inhibitors for the treatment of e.g. Irritable Bowel Syndrome (IBS) | 豪夫迈·罗氏有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-111989327-A | Compounds for the treatment of pain | 奥克梅斯公司 | 2020-11-24 | — | — | CN | disclosed |
| CN-107922379-B | Substituted guanidine derivatives | 宇部兴产株式会社 | 2020-11-06 | — | — | CN | disclosed |
| CN-111902411-A | Compositions and methods for expanding hematopoietic stem and progenitor cells and treating inherited metabolic disorders | 美真达治疗公司 | 2020-11-06 | — | — | CN | disclosed |
| WO-2020195656-A1 | FORMED BODY AND PRODUCTION METHOD THEREFOR | 株式会社ダイセル | 2020-10-01 | — | — | WO | disclosed |
| CN-111727185-A | Substituted N-heterocyclyl-and N-heteroaryltetrahydropyrimidines and their salts and their use as herbicidal active substances | 拜耳公司 | 2020-09-29 | — | — | CN | disclosed |
| CN-111655681-A | Heterocyclylamino-substituted triazoles as modulators of Rho-associated protein kinase | 莱德克斯制药公共有限公司 | 2020-09-11 | — | — | CN | disclosed |
| CN-111542597-A | Compositions and methods for expanding hematopoietic stem and progenitor cells | 美真达治疗公司 | 2020-08-14 | — | — | CN | disclosed |
| CN-107106569-B | Composition comprising a metal oxide and a metal oxide | 兴和株式会社 | 2020-07-28 | — | — | CN | disclosed |
| CN-110770214-A | Heterocyclic P2X7 antagonists | 阿克萨姆股份公司 | 2020-02-07 | — | — | CN | disclosed |
| WO-2020011731-A1 | SPIROCYCLIC INDANE ANALOGUES AS IL-17 MODULATORS | UCB Biopharma SRL (BE) | 2020-01-16 | — | — | WO | disclosed |
| WO-2020004521-A1 | THERAPEUTIC AGENT FOR INFLAMMATORY DISEASES, AUTOIMMUNE DISEASES, FIBROTIC DISEASES, AND CANCER DISEASES | Ｍｅｉｊｉ Ｓｅｉｋａファルマ株式会社 | 2020-01-02 | — | — | WO | disclosed |
| WO-2019233440-A1 | COMPOUND FOR TREATMENT OR PREVENTION OF LIVER DISEASES | 江苏新元素医药科技有限公司 (CN) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019183246-A1 | COMPOSITIONS AND METHODS OF FAS INHIBITION | ONL THERAPEUTICS, INC. (US) | 2019-09-26 | — | — | WO | disclosed |
| US-20190201500-A1 | COMPOSITIONS AND METHODS OF FAS INHIBITION | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2019-07-04 | — | — | US | disclosed |
| EP-3497101-A1 | SUBSTITUTED 2-HETEROCYCLYL IMIDAZOLYL-CARBOXAMIDES AS PEST CONTROL AGENTS | Bayer CropScience Aktiengesellschaft (DE) | 2019-06-19 | — | — | EP | disclosed |
| CN-101876789-B | Positive photo-sensitive resin composition and solidification film forming method using same | FUJIFILM | 2013-10-30 | — | — | CN | disclosed |
| CN-101876791-B | Positive photo-resist resin composition and solidification film forming method using the composition | FUJIFILM | 2013-06-12 | — | — | CN | disclosed |
| CN-103080106-A | Cyclic ether compounds useful as kinase inhibitors | NOVARTIS AG | 2013-05-01 | — | — | CN | disclosed |
| CN-102225998-A | Preparation method for pentaerythritol phosphoryl triethanolamide | ZHEJIANG KEFENG CHEMICAL CO LTD | 2011-10-26 | — | — | CN | disclosed |
| CN-102117013-A | Photoresist composition | SUMITOMO CHEMICAL CO | 2011-07-06 | — | — | CN | disclosed |
| CN-101684166-A | Resin and chemically amplified resist composition comprising the same | SUMITOMO CHEMICAL CO | 2010-03-31 | — | — | CN | disclosed |
| CN-100351257-C | Method for producing pyridoxine or an acid addition salt thereof | BASF AG (DE) | 2007-11-28 | — | — | CN | disclosed |
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| CN-1305852-C | Diaryl ethers as opioid receptor antagonists | LILLY CO ELI (US) | 2007-03-21 | — | — | CN | disclosed |
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| CN-1382045-A | Inhibitor for 20-hydroxy-eicosatetraenoic acid enzyme | TAISHO PHARMACEUTICAL CO LTD (JP) | 2002-11-27 | — | — | CN | disclosed |
| CN-1349404-A | Utilization of polycyclic 2-amino-thiazole systems in the production of medicaments for prophylaxis treatment of obesity | AVENTIS PHARMA GMBH (DE) | 2002-05-15 | — | — | CN | disclosed |
| CN-1344263-A | Polycyclic 2-aimino-thiazole systems, method for prodn. thereof and medicament contg. said compounds | AVENTIS PHARMA GMBH (DE) | 2002-04-10 | — | — | CN | disclosed |
| CN-1309653-A | Polycyclic thiazolidin-2-ylidene amines, method for production and use thereof as medicaments | AVENTIS PHARMA GMBH (DE) | 2001-08-22 | — | — | CN | disclosed |
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