SCHEMBL21056992

SCHEMBL21056992

O=C(O)C(CF)Oc1ccc(Cl)cc1-c1ccon1

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.44
PPARG P37231 6/20 0.44
F11 P03951 5/20 0.36
KLKB1 P03952 4/20 0.36
SCN9A Q15858 2/20 0.35
TSHR P16473 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
PTGDR2 Q9Y5Y4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21056990 1.00 PPARA (0.44) PPARAPPARGF11KLKB1SCN9A
SCHEMBL21057016 0.88 PPARA (0.42) PPARAPPARGF11KLKB1SCN9A
SCHEMBL21057018 0.88 PPARA (0.42) PPARAPPARGF11KLKB1SCN9A
SCHEMBL31758941 0.86 PPARA (0.40) PPARAPPARGF11KLKB1SCN9A
SCHEMBL21057001 0.86 PTGDR2 (0.34) PPARAPPARGPTGDR2
SCHEMBL21057003 0.86 PTGDR2 (0.34) PPARAPPARGPTGDR2
SCHEMBL21057015 0.84 PPARA (0.39) PPARAPPARGF11KLKB1SCN9A
SCHEMBL21057017 0.84 PPARA (0.39) PPARAPPARGF11KLKB1SCN9A
SCHEMBL21056969 0.84 PPARA (0.37) PPARAPPARG
SCHEMBL21056966 0.84 PPARA (0.37) PPARAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111712489-B Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2023-11-07 CN claimed
EP-3724173-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2021-09-22 EP claimed
CN-111712489-A Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2020-09-25 CN claimed
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
US-12440477-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2025-10-14 US disclosed
CN-111712489-B Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2023-11-07 CN disclosed
EP-3724173-B1 COMPOUNDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2021-09-22 EP disclosed
CN-111712489-A Compounds for the treatment of neuromuscular disorders NMD制药股份公司 2020-09-25 CN disclosed
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12440477-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885F11 1805/4885
US-20190183863-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885PPARG 3332/4885F11 1805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.