SCHEMBL21057243

SCHEMBL21057243

O=C(O)C(CCF)Oc1ccc(Br)cc1I

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 11/20 0.39
LDHA P00338 1/20 0.38
PPARG P37231 9/20 0.38
PTGDR2 Q9Y5Y4 6/20 0.35
MMP1 P03956 1/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35
KMT2A Q03164 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21057242 1.00 PPARA (0.39) PPARALDHAPPARGPTGDR2MMP1
SCHEMBL21057151 0.84 PPARA (0.49) PPARAPPARGPTGDR2
SCHEMBL21057154 0.84 PPARA (0.49) PPARAPPARGPTGDR2
SCHEMBL21057136 0.84 SMN1; SMN2 (0.47) PPARALDHAPPARGPTGDR2MMP1
SCHEMBL21057133 0.84 SMN1; SMN2 (0.47) PPARALDHAPPARGPTGDR2MMP1
SCHEMBL21057207 0.83 PPARA (0.49) PPARAPPARGMEN1TSHRKMT2A
SCHEMBL21057208 0.83 PPARA (0.49) PPARAPPARGMEN1TSHRKMT2A
SCHEMBL21060484 0.80 PTGDR2 (0.41) PPARAPPARGPTGDR2MMP1MEN1
SCHEMBL28676299 0.79 PTGDR2 (0.45) PPARAPPARGPTGDR2MMP1
SCHEMBL28676300 0.79 PTGDR2 (0.45) PPARAPPARGPTGDR2MMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN claimed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
EP-3723745-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2024-06-19 EP disclosed
US-11730714-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-08-22 US disclosed
EP-3723745-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP disclosed
CN-111587109-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-25 CN disclosed
WO-2019115777-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11730714-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, RYR2 PPARA 3247/4885LDHA 2645/4885PPARG 3332/4885
US-20190183834-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PPARA 3247/4885LDHA 2645/4885PPARG 3332/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.