SCHEMBL21059445

SCHEMBL21059445

C[C@H](Oc1ccc(Br)cc1C1CCC1)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PTGDR2 Q9Y5Y4 10/20 0.67
PTGDR Q13258 5/20 0.67
TSHR P16473 1/20 0.43
HTR2A P28223 1/20 0.43
HTR2C P28335 1/20 0.43
HTR2B P41595 1/20 0.43
KMT2A Q03164 1/20 0.40
PPARG P37231 1/20 0.39
PPARD Q03181 1/20 0.39
PPARA Q07869 1/20 0.39
SMN1; SMN2 Q16637 3/20 0.38
LMNA P02545 1/20 0.38
ATM Q13315 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
PTGER2 P43116 1/20 0.38
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21059447 1.00 PTGDR2 (0.67) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL28444725 0.99 PTGDR2 (0.65) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL28444727 0.99 PTGDR2 (0.65) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL21059483 0.94 PTGDR2 (0.62) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL21059486 0.94 PTGDR2 (0.62) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL30287858 0.87 PTGDR2 (0.51) PTGDR2PTGDRTSHRKMT2ASMN1; SMN2
SCHEMBL21059478 0.84 PTGDR2 (0.92) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL21059492 0.84 PTGDR2 (0.67) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL21059491 0.84 PTGDR2 (0.67) PTGDR2PTGDRTSHRHTR2AHTR2C
SCHEMBL21059480 0.84 PTGDR2 (0.92) PTGDR2PTGDRTSHRHTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP claimed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO claimed
CN-111491628-B Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2023-10-13 CN claimed
US-11591284-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-02-28 US claimed
EP-3723746-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2022-02-23 EP claimed
EP-3723746-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD Pharma A/S (DK) 2020-10-21 EP claimed
CN-111491628-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-04 CN claimed
WO-2019115780-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO claimed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US claimed
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US claimed
EP-4731200-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD Pharma A/S (DK) 2026-04-29 EP disclosed
WO-2024261020-A1 CLC-1 INHIBITORS FOR USE IN THE TREATMENT OF MULTIPLE SCLEROSIS AND NEUROMUSCULAR DISEASES NMD PHARMA A/S (DK) 2024-12-26 WO disclosed
CN-111491628-B Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2023-10-13 CN disclosed
US-11591284-B2 Compounds for the treatment of neuromuscular disorders NMD PHARMA A/S (DK) 2023-02-28 US disclosed
EP-3723746-B1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA AS (DK) 2022-02-23 EP disclosed
CN-111491628-A Phenoxy acids for the treatment of neuromuscular disorders NMD制药股份公司 2020-08-04 CN disclosed
WO-2019115780-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
WO-2019115780-A1 PHENOXY ACIDS FOR THE TREATMENT OF NEUROMUSCULAR DISORDERS NMD PHARMA A/S (DK) 2019-06-20 WO disclosed
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA A/S (DK) 2019-06-20 US disclosed
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders NMD PHARMA APS (DK) 2019-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185409-A1 Compounds For The Treatment Of Neuromuscular Disorders CPT1B, CLCN2, CACNB1 PTGDR2 1344/4885PTGDR 1130/4885TSHR 3912/4885
US-20190183812-A1 Compounds For The Treatment Of Neuromuscular Disorders RYR1, CACNB1, RYR2 PTGDR2 2581/4885PTGDR 2725/4885TSHR 3626/4885
US-11591284-B2 Compounds for the treatment of neuromuscular disorders RYR1, CACNB1, CACNA1S PTGDR2 1624/4885PTGDR 1550/4885TSHR 4324/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.