⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL210598 | 1.00 | — | — | |
| SCHEMBL223376 | 1.00 | — | — | |
| SCHEMBL5026514 | 0.86 | — | — | |
| SCHEMBL2999352 | 0.86 | — | — | |
| SCHEMBL4381020 | 0.86 | — | — | |
| SCHEMBL2984642 | 0.85 | CREBBP (0.36) | — | |
| SCHEMBL31048256 | 0.85 | CREBBP (0.36) | — | |
| SCHEMBL157216 | 0.82 | — | — | |
| SCHEMBL2984521 | 0.82 | — | — | |
| SCHEMBL1649789 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1289 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250066296-A1 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2025-02-27 | — | — | US | claimed |
| CN-119192561-A | Preparation method of melting point-adjustable polybutylece lactam copolymer | 上海簇睿低碳能源技术有限公司 | 2024-12-27 | — | — | CN | claimed |
| EP-4448490-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | Alexion Pharmaceuticals, Inc. (US) | 2024-10-23 | — | — | EP | claimed |
| CN-118382616-A | Synthesis method of complement factor D inhibitor and intermediate thereof | 阿雷克森制药公司 | 2024-07-23 | — | — | CN | claimed |
| US-20230398526-A1 | NITROGEN HETEROCYCLIC CARBENE CATALYST AND PREPARATION METHOD THEREFOR | PINGSHAN TRANSLATIONAL MEDICINE CENTER, SHENZHEN BAY LABORATOR (CN) | 2023-12-14 | — | — | US | claimed |
| WO-2023114200-A2 | METHODS FOR THE SYNTHESIS OF COMPLEMENT FACTOR D INHIBITORS AND INTERMEDIATES THEREOF | ALEXION PHARMACEUTICALS, INC. (US) | 2023-06-22 | — | — | WO | claimed |
| CN-106684389-A | Sulfur-nitrogen dual-doped graphene nano material and preparation method and application thereof | 温州大学 | 2017-05-17 | — | — | CN | claimed |
| US-7049446-B2 | Process for chemical reaction of amino acids and amides yielding selective conversion products | BATTELLE MEMORIAL INSTITUTE (US) | 2006-05-23 | — | — | US | claimed |
| US-20040225133-A1 | Process for chemical reaction of amino acids and amides yielding selective conversion products | BATTELLE MEMORIAL INSTITUTE | 2004-11-11 | — | — | US | claimed |
| EP-0443923-B1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI SA (FR) | 1997-08-27 | — | — | EP | claimed |
| EP-0443923-A1 | New aminophosphine-phosphinites, their process and their use for enantio-selective reactions | SANOFI (FR) | 1991-08-28 | — | — | EP | claimed |
| JP-61207392-A | — | — | None | — | — | JP | disclosed |
| US-20260137703-A1 | 2-AMINO-PYRIDO[2,3-D]PYRIMIDIN-7(8H)-ONE AND 7-AMINO-1-PYRIMIDO[4,5-D]PYRIMIDIN-2(1 H)-ONE DERIVATIVES AS EGFR INHIBITORS FOR THE TREATMENT OF CANCER | CANCER RESEARCH TECH LIMITED (GB) | 2026-05-21 | — | — | US | disclosed |
| CN-122070282-A | Pyrazole-1-carboxamides as RIP1 kinase inhibitors | 比西切姆有限公司 | 2026-05-19 | — | — | CN | disclosed |
| US-12630562-B2 | Piperidylurea compounds and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2026-05-19 | — | — | US | disclosed |
| EP-0334244-A2 | Bradykinin Antagonist Peptides | THE PROCTER & GAMBLE COMPANY (US) | 1989-09-27 | — | — | EP | disclosed |
| US-4621145-A | Process for preparing 5-vinyl-2-pyrrolidinone and intermediates therefor | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-11-04 | — | — | US | disclosed |
| JP-S61207392-A | PYRROLIDONE DERIVATIVE AND PRODUCTION THEREOF | AJINOMOTO CO INC | 1986-09-13 | — | — | JP | disclosed |
| EP-0116257-B1 | PROCESS FOR PREPARING 4-AMINO-5-HEXENOIC ACID | MERRELL DOW FRANCE ET CIE (FR) | 1986-08-27 | — | — | EP | disclosed |
| US-4177346-A | 1,5-Disubstituted-2-pyrrolidones | PFIZER INC. (US) | 1979-12-04 | — | — | US | disclosed |