⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14128272 | 1.00 | — | — | |
| Formaldehyde SCHEMBL27838123 | 0.93 | MEN1 (0.40) | — | |
| SCHEMBL27861243 | 0.89 | MEN1 (0.38) | — | |
| SCHEMBL30456784 | 0.83 | — | — | |
| SCHEMBL16487535 | 0.72 | SMN1; SMN2 (0.42) | — | |
| SCHEMBL147208 | 0.72 | — | — | |
| SCHEMBL25087089 | 0.72 | — | — | |
| SCHEMBL22719968 | 0.72 | — | — | |
| SCHEMBL19224193 | 0.72 | — | — | |
| SCHEMBL1066584 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4359368-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WockLab GmbH & Co. KG (DE) | 2024-05-01 | — | — | EP | claimed |
| US-11919839-B2 | Alpha-cinnamide compounds and compositions as HDAC8 inhibitors | VALO HEALTH, INC. (US) | 2024-03-05 | — | — | US | claimed |
| WO-2022268777-A1 | COMBINATION OF A PYRAZOLE AND A THIOPHOSPHORIC TRIAMIDE | WOCKLAB GMBH & CO. KG (DE) | 2022-12-29 | — | — | WO | claimed |
| CN-114634456-A | 5-nitroimino-4H-1, 2, 4-triazole compound and preparation method and application thereof | 赣南师范大学 | 2022-06-17 | — | — | CN | claimed |
| US-20220073452-A1 | ALPHA-CINNAMIDE COMPOUNDS AND COMPOSITIONS AS HDAC8 INHIBITORS | VALO HEALTH, INC. | 2022-03-10 | — | — | US | claimed |
| CN-103613583-A | 1, 3-substituent-4-substituted pyrazol acylhydrazone derivative and preparation method and application thereof | UNIV GUIZHOU | 2014-03-05 | — | — | CN | claimed |
| EP-0294238-B1 | NOVEL 1-ALKYL-1-SULFONYL-2-ALKOXYCARBONYLSULFENYLHYDRAZINES HAVING ANTINEOPLASTIC ACTIVITY | YALE UNIVERSITY (US) | 1992-08-26 | — | — | EP | claimed |
| US-4962114-A | ANTITUMOR AGENTS; ALKYLATING AGENTS; NONTOXIC | YALE UNIVERSITY (US) | 1990-10-09 | — | — | US | claimed |
| EP-0294238-A1 | Novel 1-alkyl-1-sulfonyl-2-alkoxycarbonylsulfenylhydrazines having antineoplastic activity | YALE UNIVERSITY (US) | 1988-12-07 | — | — | EP | claimed |
| EP-3351533-B1 | BIARYL DERIVATIVE AND MEDICINE CONTAINING SAME | KAKEN PHARMA CO LTD (JP) | 2025-07-23 | — | — | EP | disclosed |
| CN-118878529-A | 2, 3-Dihydro-oxazole compound containing 1, 3-dithiane and preparation method thereof | 兰州大学 | 2024-11-01 | — | — | CN | disclosed |
| US-RE50082-E1 | (5,6-dihydro)pyrimido[4,5-e]indolizines | NETHERLANDS TRANSLATIONAL RESEARCH CENTER B.V. (NL) | 2024-08-20 | — | — | US | disclosed |
| US-20240228472-A1 | HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-11 | — | — | US | disclosed |
| US-20240228472-A1 | HETEROCYCLIC COMPOUND AND HARMFUL-ARTHROPOD-CONTROLLING COMPOSITION CONTAINING SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2024-07-11 | — | — | US | disclosed |
| EP-0087780-A2 | Pyrazolesulfonylurea derivative, preparation thereof, herbicide containing said derivative as active ingredient and herbicidal method by use thereof | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1983-09-07 | — | — | EP | disclosed |
| US-4301293-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LTD. (JP) | 1981-11-17 | — | — | US | disclosed |
| US-4261729-A | Herbicidal compositions and pyrazole derivatives | SANKYO COMPANY LIMITED (JP) | 1981-04-14 | — | — | US | disclosed |
| US-4146726-A | HERBICIDES | SANKYO COMPANY LIMITED (JP) | 1979-03-27 | — | — | US | disclosed |
| US-4077956-A | ANTIINFLAMMATORY, IMMUNOSUPPRESSIVE | E. R. SQUIBB & SONS, INC. (US) | 1978-03-07 | — | — | US | disclosed |
| US-4063925-A | Herbicidal compositions | SANKYO COMPANY LIMITED (JA) | 1977-12-20 | — | — | US | disclosed |