Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15178946 | 0.85 | HDAC8 (0.36) | HDAC8MAPTBRD4 | |
| SCHEMBL15178892 | 0.85 | HDAC8 (0.36) | HDAC8MAPTBRD4 | |
| SCHEMBL15178947 | 0.85 | HDAC8 (0.36) | HDAC8MAPTBRD4 | |
| SCHEMBL15178997 | 0.85 | HDAC8 (0.36) | HDAC8MAPTBRD4 | |
| SCHEMBL15178941 | 0.76 | BRD4 (0.32) | HDAC8MAPTBRD4 | |
| SCHEMBL15178925 | 0.76 | BRD4 (0.34) | HDAC8MAPTBRD4 | |
| SCHEMBL15178926 | 0.76 | BRD4 (0.34) | HDAC8MAPTBRD4 | |
| SCHEMBL15178936 | 0.76 | BRD4 (0.34) | HDAC8MAPTBRD4 | |
| SCHEMBL15178884 | 0.76 | BRD4 (0.34) | HDAC8MAPTBRD4 | |
| SCHEMBL15178924 | 0.76 | BRD4 (0.34) | HDAC8MAPTBRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2222654-B1 | 2-METHYLTHIOETHYL-SUBSTITUTED HEYRROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| EP-2222654-B1 | 2-METHYLTHIOETHYL-SUBSTITUTED HEYRROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2013-03-20 | — | — | EP | disclosed |
| US-8158186-B2 | 2-methylthioethyl-substituted heterocycles as feed additives | EVONIK DEGUSSA GMBH (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8158186-B2 | 2-methylthioethyl-substituted heterocycles as feed additives | EVONIK DEGUSSA GMBH (DE) | 2012-04-17 | — | — | US | disclosed |
| US-8158186-B2 | 2-methylthioethyl-substituted heterocycles as feed additives | EVONIK DEGUSSA GMBH (DE) | 2012-04-17 | — | — | US | disclosed |
| EP-2222654-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HEYRROCYCLES AS FEED ADDITIVES | Evonik Degussa GmbH (DE) | 2010-09-01 | — | — | EP | disclosed |
| WO-2009080446-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HEYRROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080446-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HEYRROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2009-07-02 | — | — | WO | disclosed |
| US-20090162474-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HETEROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090162474-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HETEROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
| US-20090162474-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HETEROCYCLES AS FEED ADDITIVES | EVONIK DEGUSSA GMBH (DE) | 2009-06-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090162474-A1 | 2-METHYLTHIOETHYL-SUBSTITUTED HETEROCYCLES AS FEED ADDITIVES | CCNL2, AKR7A2, AGXT | HDAC8 2654/4885MAPT 3587/4885BRD4 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.