Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 9/20 | 0.43 |
| ▸ | PPARA | Q07869 | 8/20 | 0.43 |
| ▸ | PPARD | Q03181 | 5/20 | 0.43 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.39 |
| ▸ | ALDH3A1 | P30838 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.38 |
| ▸ | TOP2A | P11388 | 3/20 | 0.38 |
| ▸ | TOP2B | Q02880 | 3/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3531013 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL3531610 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL3532175 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL3528148 | 0.82 | PPARG (0.48) | PPARGPPARAPPARDALDH3A1KDM4E | |
| SCHEMBL23436432 | 0.82 | PPARG (0.43) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL7213488 | 0.81 | PPARG (0.48) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL21064305 | 0.81 | PPARG (0.47) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL16235830 | 0.80 | PPARG (0.46) | PPARGPPARAPPARDNOD1ALDH3A1 | |
| SCHEMBL3535429 | 0.79 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL3535449 | 0.79 | PPARG (0.56) | PPARGPPARAPPARDNOD1ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11254671-B2 | Chemical compounds | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2022-02-22 | — | — | US | disclosed |
| US-20210163472-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2021-06-03 | — | — | US | disclosed |
| EP-3724187-A1 | 6-(MORPHOLIN-4-YL)-PYRIDIN-2-YL-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS M-TOR INHIBITORS | GlaxoSmithKline Intellectual Property Development Limited (GB) | 2020-10-21 | — | — | EP | disclosed |
| WO-2019115640-A1 | 6-(MORPHOLIN-4-YL)-PYRIDIN-2-YL-1H-PYRROLO[3,2-B]PYRIDINE DERIVATIVES AS M-TOR INHIBITORS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2019-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210163472-A1 | CHEMICAL COMPOUNDS | MTOR, RICTOR, RPTOR | PPARG 2397/4885PPARA 2567/4885PPARD 2844/4885 |
| US-11254671-B2 | Chemical compounds | MTOR, RICTOR, RPTOR | PPARG 2397/4885PPARA 2567/4885PPARD 2844/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.