Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20865562 | 0.92 | TSHR (0.71) | TSHRBTKHCRTR2EPHX1CTSK | |
| SCHEMBL18941450 | 0.89 | TSHR (0.60) | TSHRBTKTDP1 | |
| SCHEMBL18941457 | 0.88 | TSHR (0.58) | TSHRTDP1 | |
| SCHEMBL18323868 | 0.84 | TSHR (0.71) | TSHREPHX1KMT2ATDP1NFKB1 | |
| SCHEMBL18433640 | 0.84 | TSHR (0.67) | TSHRTDP1 | |
| SCHEMBL13199418 | 0.83 | TSHR (0.64) | TSHRKMT2AGAATDP1 | |
| SCHEMBL18323867 | 0.83 | TSHR (0.65) | TSHRTDP1 | |
| SCHEMBL22476427 | 0.82 | TSHR (0.52) | TSHR | |
| SCHEMBL20232089 | 0.82 | TSHR (0.64) | TSHRTDP1HSD11B1 | |
| SCHEMBL15850695 | 0.81 | TSHR (0.66) | TSHREPHX1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3233790-B1 | CHEMICAL BLOWING AGENT AND THERMALLY EXPANDABLE THERMOPLASTIC COMPOSITION | SIKA TECH AG (CH) | 2019-06-26 | — | — | EP | disclosed |