⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL190135 | 0.70 | — | — | |
| SCHEMBL5238830 | 0.70 | — | — | |
| SCHEMBL12151185 | 0.67 | — | — | |
| SCHEMBL8028896 | 0.67 | — | — | |
| SCHEMBL11211819 | 0.67 | — | — | |
| SCHEMBL11959551 | 0.67 | — | — | |
| Bicarbonate SCHEMBL29569190 | 0.65 | — | — | |
| SCHEMBL8180839 | 0.63 | — | — | |
| SCHEMBL815 | 0.60 | — | — | |
| SCHEMBL9181149 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8039501-B2 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2011-10-18 | — | — | US | claimed |
| US-20090029999-A1 | Synephrine derivatives useful as anti-inflammatory agents | UNIVERSITEIT GENT (BE) | 2009-01-29 | — | — | US | claimed |
| EP-1963255-A1 | SYNEPHRINE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIVERSITEIT GENT (BE) | 2008-09-03 | — | — | EP | claimed |
| WO-2007071452-A1 | SYNEPHRINE DERIVATIVES USEFUL AS ANTI-INFLAMMATORY AGENTS | UNIVERSITEIT GENT (BE) | 2007-06-28 | — | — | WO | claimed |
| US-4994503-A | Stable dispersion of polymer containing aminocarbonyl and aminothiocarbonyl groups in a continuous phase; reinforcement and fillers of polyurethane and/or-urea matrix | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | claimed |
| US-4522763-A | STARTING MATERIALS FOR CROP PROTECTION AGENTS AND SELECTIVE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | claimed |
| EP-0073442-B1 | N-ALKOXYCARBONYL AND N-ALKOXYTHIOCARBONYL AMIDINES AND PREPARATION THEREOF | BASF Aktiengesellschaft (DE) | 1985-03-13 | — | — | EP | claimed |
| EP-4043463-B1 | FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY | SHIONOGI & CO (JP) | 2025-11-26 | — | — | EP | disclosed |
| US-12454533-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2025-10-28 | — | — | US | disclosed |
| US-20240309002-A1 | FUSED RING DERIVATIVE HAVING MGAT-2 INHIBITORY ACTIVITY | SHIONOGI & CO., LTD. (JP) | 2024-09-19 | — | — | US | disclosed |
| US-12024519-B2 | Fused ring derivative having MGAT-2 inhibitory activity | SHIONOGI & CO., LTD. (JP) | 2024-07-02 | — | — | US | disclosed |
| CN-113501821-B | Fused ring derivatives having MGAT-2 inhibitory activity | 盐野义制药株式会社 | 2024-04-09 | — | — | CN | disclosed |
| CN-111094288-B | Fused ring derivatives having MGAT-2 inhibitory activity | 盐野义制药株式会社 | 2022-12-23 | — | — | CN | disclosed |
| US-4994503-A | Stable dispersion of polymer containing aminocarbonyl and aminothiocarbonyl groups in a continuous phase; reinforcement and fillers of polyurethane and/or-urea matrix | THE DOW CHEMICAL COMPANY (US) | 1991-02-19 | — | — | US | disclosed |
| US-4881965-A | CONTROLLING WILD OATS | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1989-11-21 | — | — | US | disclosed |
| EP-0318602-A1 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1989-06-07 | — | — | EP | disclosed |
| EP-0189069-A2 | Pyrazolesulfonamide derivative, process for its production and herbicide containing it | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1986-07-30 | — | — | EP | disclosed |
| US-4522763-A | STARTING MATERIALS FOR CROP PROTECTION AGENTS AND SELECTIVE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
| US-4522763-A | STARTING MATERIALS FOR CROP PROTECTION AGENTS AND SELECTIVE HERBICIDES | BASF AKTIENGESELLSCHAFT (DE) | 1985-06-11 | — | — | US | disclosed |
| US-4327034-A | CHEMICAL INTERMEDIATE PREPARED FROM A SULFAMIC ACID HALIDE AND A HALOGEN COMPOUND | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |