Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.43 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21066095 | 0.84 | TSHR (0.37) | TSHRPTPN1RETMAOB | |
| SCHEMBL21065810 | 0.82 | CYP2A6 (0.44) | — | |
| SCHEMBL21066138 | 0.79 | TEAD1 (0.39) | TSHR | |
| SCHEMBL13365531 | 0.77 | PTPN1 (0.45) | TSHRPTPN1KDM4ERIPK1 | |
| SCHEMBL1979984 | 0.76 | TSHR (0.43) | TSHRPTPN1RETPPARGPPARA | |
| SCHEMBL3680893 | 0.76 | TSHR (0.43) | TSHRPTPN1RETPPARGPPARA | |
| SCHEMBL4726112 | 0.76 | TSHR (0.43) | TSHRPTPN1RETPPARGPPARA | |
| SCHEMBL1026267 | 0.76 | TSHR (0.57) | TSHRPTPN1RETPPARGPPARA | |
| SCHEMBL12305007 | 0.76 | TSHR (0.57) | TSHRPTPN1RETPPARGPPARA | |
| SCHEMBL12896348 | 0.72 | TSHR (0.53) | TSHRPTPN1RETPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3497101-B1 | SUBSTITUTED 2-HETEROCYCLYL IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2020-12-30 | — | — | EP | disclosed |
| US-10660333-B2 | Substituted 2-heterocyclylimidazolylcarboxamides as pesticides | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2020-05-26 | — | — | US | disclosed |
| US-20190166837-A1 | SUBSTITUTED 2-HETEROCYCLYLIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190166837-A1 | SUBSTITUTED 2-HETEROCYCLYLIMIDAZOLYLCARBOXAMIDES AS PESTICIDES | DDT, PTMS, TSNAX | TSHR 639/4885PTPN1 2025/4885RET 3267/4885 |
| US-10660333-B2 | Substituted 2-heterocyclylimidazolylcarboxamides as pesticides | DDT, PTMS, TSNAX | TSHR 639/4885PTPN1 2025/4885RET 3267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.