Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.47 |
| ▸ | DPP4 | P27487 | 8/20 | 0.46 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.46 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.46 |
| ▸ | DPP7 | Q9UHL4 | 5/20 | 0.46 |
| ▸ | FAP | Q12884 | 4/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | XIAP | P98170 | 1/20 | 0.43 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.43 |
| ▸ | TACR1 | P25103 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL13732949 | 1.00 | HDAC8 (0.47) | HDAC8DPP4DPP8DPP9DPP7 | |
| SCHEMBL13827832 | 0.94 | HDAC8 (0.52) | HDAC8DPP4DPP8DPP9DPP7 | |
| SCHEMBL14857050 | 0.94 | HDAC8 (0.52) | HDAC8DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL14762499 | 0.91 | SLC7A5 (0.46) | HDAC8DPP4DPP8DPP9DPP7 | |
| SCHEMBL14856940 | 0.90 | HDAC8 (0.54) | HDAC8DPP4DPP8DPP9DPP7 | |
| Trifluoroacetic Acid SCHEMBL16394303 | 0.90 | DPP7 (0.49) | DPP4DPP8DPP9DPP7FAP | |
| Trifluoroacetic Acid SCHEMBL21066050 | 0.82 | KDM4E (0.53) | DPP4TACR1L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL13732393 | 0.82 | KDM4E (0.53) | DPP4TACR1L3MBTL1 | |
| SCHEMBL21066047 | 0.82 | HDAC8 (0.51) | HDAC8DPP4DPP8DPP9DPP7 | |
| SCHEMBL21066046 | 0.82 | HDAC8 (0.51) | HDAC8DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3501546-A2 | CYSTEINE DRUG CONJUGATES AND USE OF SAME | Seattle Genetics, Inc. (US) | 2019-06-26 | — | — | EP | disclosed |