Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 1/20 | 0.57 |
| ▸ | DNM1 | Q05193 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL26105978 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Bromide SCHEMBL394568 | 1.00 | — | — | |
| Bromide SCHEMBL596230 | 1.00 | TSHR (0.57) | TSHRTHRBDNM1ALDH1A1LMNA | |
| Bromide SCHEMBL5512945 | 1.00 | — | — | |
| SCHEMBL8136903 | 0.96 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL5696337 | 0.96 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL28436423 | 0.96 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL1576030 | 0.96 | — | — | |
| SCHEMBL21835154 | 0.96 | TSHR (0.61) | TSHRTHRBDNM1ALDH1A1LMNA | |
| SCHEMBL964127 | 0.96 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220332870-A1 | Narrow Band Gap Conjugated Polymers Employing Cross-Conjugated Donors Useful In Electronic Devices | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2022-10-20 | — | — | US | disclosed |
| US-11312819-B2 | Narrow band gap conjugated polymers employing cross-conjugated donors useful in electronic devices | THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) | 2022-04-26 | — | — | US | disclosed |
| CN-110214204-A | Narrow bandgap conjugated polymers using cross-conjugated donors for electronic devices | 杰森·D·阿祖莱 | 2019-09-06 | — | — | CN | disclosed |
| US-20190194385-A1 | Narrow Band Gap Conjugated Polymers Employing Cross-Conjugated Donors Useful in Electronic Devices | THE UNIVERSITY OF SOUTHERN MISSISSIPPI | 2019-06-27 | — | — | US | disclosed |
| CN-104822662-B | New sulfonic acid compound, photoacid generator, cationic polymerization initiators, anti-corrosion agent composition and cationically polymerizable composition | 株式会社ADEKA | 2018-04-03 | — | — | CN | disclosed |
| CN-104822662-A | Novel sulfonic acid derivative compound, photoacid generator, cationic polymerization initiator, resist composition, and cationically polymerizable composition | ADEKA CORP | 2015-08-05 | — | — | CN | disclosed |