Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 1.00 |
| ▸ | INSR | P06213 | 2/20 | 0.77 |
| ▸ | IGF1R | P08069 | 2/20 | 0.77 |
| ▸ | GSK3B | P49841 | 10/20 | 0.76 |
| ▸ | GSK3A | P49840 | 7/20 | 0.76 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | BLM | P54132 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.67 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.67 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.59 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1064248 | 0.88 | IGF1R (0.80) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL1064250 | 0.88 | IGF1R (0.80) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL3363802 | 0.88 | IGF1R (0.80) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL12989670 | 0.87 | IGF1R (1.00) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL3363658 | 0.87 | IGF1R (1.00) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL3363656 | 0.87 | IGF1R (1.00) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL6721235 | 0.86 | GSK3B (1.00) | CDK2INSRIGF1RGSK3BGSK3A | |
| SCHEMBL623104 | 0.86 | CDK2 (0.76) | CDK2IGF1RGSK3BGSK3AMEN1 | |
| SCHEMBL623103 | 0.86 | CDK2 (0.76) | CDK2IGF1RGSK3BGSK3AMEN1 | |
| SCHEMBL13479541 | 0.84 | CDK2 (0.72) | CDK2IGF1RGSK3BGSK3AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4256086-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | Cedars-Sinai Medical Center (US) | 2023-10-11 | — | — | EP | disclosed |
| WO-2022119842-A1 | METHODS AND SYSTEMS OF STRATIFYING INFLAMMATORY DISEASE PATIENTS | CEDARS-SINAI MEDICAL CENTER (US) | 2022-06-09 | — | — | WO | disclosed |
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |