Sugi Predict

Sugi Predict / Compounds / SCHEMBL21067337

SCHEMBL21067337

SCHEMBL21067337

NCC1CCN(CC(=O)Nc2cccc3c2C(=O)c2c-3n[nH]c2C2CCCCC2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ CCNE2 O96020 19/20 1.00
▸ CCNE1 P24864 19/20 1.00
▸ CDK2 P24941 19/20 1.00
▸ CDK4 P11802 12/20 1.00
▸ CCND1 P24385 12/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4027131 0.84 CCNE2 (1.00) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4027357 0.84 CCNE2 (1.00) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4031432 0.80 CCNE2 (0.88) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4029477 0.80 CCNE2 (0.88) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4023823 0.79 CCNE2 (0.89) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4026202 0.79 CCNE2 (0.76) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4027143 0.78 CCNE2 (0.73) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4023926 0.77 CCNE2 (0.73) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4029490 0.77 CCNE2 (1.00) CCNE2CCNE1CDK2CDK4CCND1
SCHEMBL4031441 0.77 CCNE2 (1.00) CCNE2CCNE1CDK2CDK4CCND1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 — — US disclosed