SCHEMBL21067397

SCHEMBL21067397

CCCOc1ccc(-c2csc(-c3ccccc3Cl)c2CC(=O)NC(=N)N)cc1

nearest known ligand 0.71

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 20/20 0.71
CTSD P07339 1/20 0.46
BACE2 Q9Y5Z0 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5803571 0.94 BACE1 (0.73) BACE1CTSDBACE2
SCHEMBL5915918 0.89 BACE1 (0.69) BACE1
SCHEMBL4805204 0.89 BACE1 (0.69) BACE1
SCHEMBL4805928 0.83 BACE1 (1.00) BACE1CTSDBACE2
SCHEMBL4812107 0.81 BACE1 (0.71) BACE1CTSDBACE2
SCHEMBL5915850 0.80 BACE1 (0.58) BACE1CTSDBACE2
SCHEMBL5915897 0.80 BACE1 (0.56) BACE1
SCHEMBL4812384 0.79 BACE1 (0.61) BACE1CTSDBACE2
SCHEMBL5804999 0.79 BACE1 (0.59) BACE1CTSDBACE2
SCHEMBL4806389 0.78 BACE1 (0.75) BACE1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed