Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | MAPT | P10636 | 6/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.64 |
| ▸ | IDE | P14735 | 1/20 | 0.58 |
| ▸ | MYC | P01106 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | PDE4A | P27815 | 1/20 | 0.50 |
| ▸ | BLVRB | P30043 | 1/20 | 0.50 |
| ▸ | KDR | P35968 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29377614 | 0.83 | MEN1 (0.74) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL25270006 | 0.83 | MEN1 (0.74) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL21067788 | 0.82 | KMT2A (0.69) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6812002 | 0.76 | MEN1 (0.62) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL21067348 | 0.76 | KMT2A (0.71) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL29021820 | 0.75 | MAPT (0.67) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6812006 | 0.75 | MEN1 (0.60) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6812010 | 0.75 | MEN1 (0.60) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6807306 | 0.75 | MEN1 (0.60) | MEN1KMT2AMAPTNPSR1GAA | |
| SCHEMBL6807307 | 0.75 | MEN1 (0.60) | MEN1KMT2AMAPTNPSR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |