SCHEMBL21067660

SCHEMBL21067660

C[C@H](N)C(=O)c1nnc(C(C)(C)C)o1

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.38
DPP4 P27487 2/20 0.34
DPP8 Q6V1X1 2/20 0.34
DPP7 Q9UHL4 1/20 0.34
CTSK P43235 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21067661 1.00 ELANE (0.38) ELANEDPP4DPP8DPP7CTSK
Hydrochloric Acid SCHEMBL5728714 0.98 ELANE (0.38) ELANEDPP4DPP8DPP7CTSK
SCHEMBL6804849 0.86 ELANE (0.39) ELANEDPP4DPP8DPP7CTSK
Hydrochloric Acid SCHEMBL6806816 0.85 ELANE (0.39) ELANEDPP4DPP8DPP7CTSK
Hydrochloric Acid SCHEMBL7129582 0.85 ELANE (0.39) ELANEDPP4DPP8DPP7CTSK
SCHEMBL2678471 0.77 DPP4 (0.36) ELANEDPP4DPP8DPP7
SCHEMBL12734314 0.75 DPP4 (0.37) ELANEDPP4DPP8DPP7
SCHEMBL8840142 0.75 PTPN1 (0.39) ELANEDPP4DPP8DPP7
SCHEMBL13300000 0.74 ELANE (0.50) ELANE
Potassium Ion SCHEMBL20532960 0.72 DPP4 (0.36) ELANEDPP4DPP8DPP7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed