Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNA2 | P20248 | 14/20 | 0.72 |
| ▸ | CDK2 | P24941 | 14/20 | 0.72 |
| ▸ | CDK5 | Q00535 | 6/20 | 0.67 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.67 |
| ▸ | MAPT | P10636 | 4/20 | 0.67 |
| ▸ | NPC1 | O15118 | 3/20 | 0.67 |
| ▸ | RAB9A | P51151 | 3/20 | 0.67 |
| ▸ | GSK3A | P49840 | 2/20 | 0.67 |
| ▸ | GSK3B | P49841 | 2/20 | 0.67 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | CLK2 | P49760 | 1/20 | 0.62 |
| ▸ | CDK9 | P50750 | 1/20 | 0.62 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.62 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.62 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.62 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1250351 | 0.81 | CCNA2 (1.00) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL1248419 | 0.80 | CCNA2 (1.00) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL4478811 | 0.78 | CCNA2 (0.76) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL31415182 | 0.77 | CDK5 (0.73) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL25609669 | 0.77 | CDK5 (0.73) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL20142253 | 0.77 | CCNA2 (0.82) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL17208610 | 0.76 | CCNA2 (0.66) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL4473692 | 0.76 | CCNA2 (0.85) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL4487974 | 0.76 | CCNA2 (0.71) | CCNA2CDK2CDK5CDK5R1MAPT | |
| SCHEMBL26459438 | 0.76 | CDK5 (0.85) | CCNA2CDK2CDK5CDK5R1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |