SCHEMBL21067784

SCHEMBL21067784

CCCC[C@@]12CCC(=O)C(Br)=C1c1ccc(O)cc1C2

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 20/20 1.00
ESR1 P03372 19/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2418015 1.00 ESR2 (1.00) ESR2ESR1
SCHEMBL4853909 0.92 ESR2 (0.85) ESR2ESR1
SCHEMBL4850382 0.91 ESR2 (0.83) ESR2ESR1
SCHEMBL4851052 0.90 ESR2 (0.81) ESR2ESR1
SCHEMBL2419638 0.87 ESR2 (1.00) ESR2ESR1
SCHEMBL2415354 0.87 ESR2 (1.00) ESR2ESR1
SCHEMBL2417758 0.86 ESR2 (1.00) ESR2ESR1
SCHEMBL2419298 0.86 ESR2 (0.76) ESR2ESR1
SCHEMBL2420019 0.86 ESR2 (0.76) ESR2ESR1
SCHEMBL2413229 0.86 ESR2 (1.00) ESR2ESR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 US disclosed