Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 20/20 | 1.00 |
| ▸ | MAPK9 | P45984 | 18/20 | 1.00 |
| ▸ | MAPK10 | P53779 | 12/20 | 1.00 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.76 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.76 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.76 |
| ▸ | PRKD2 | Q9BZL6 | 2/20 | 0.74 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.74 |
| ▸ | CDK2 | P24941 | 1/20 | 0.74 |
| ▸ | RPS6KB2 | Q9UBS0 | 1/20 | 0.74 |
| ▸ | RPS27 | P42677 | 1/20 | 0.63 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.60 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.60 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.60 |
| ▸ | STK17A | Q9UEE5 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1145450 | 0.92 | MAPK8 (0.84) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1145176 | 0.87 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1145456 | 0.86 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1146335 | 0.86 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1145517 | 0.86 | MAPK8 (0.81) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL12221577 | 0.85 | MAPK8 (0.80) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1145327 | 0.85 | MAPK8 (0.86) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL157014 | 0.85 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL29405886 | 0.85 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 | |
| SCHEMBL1145221 | 0.85 | MAPK8 (1.00) | MAPK8MAPK9MAPK10MAPK1PRKD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |