Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP2K1 | Q02750 | 17/20 | 0.46 |
| ▸ | MAP2K2 | P36507 | 13/20 | 0.46 |
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | MAP2K5 | Q13163 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.38 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.38 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.38 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.38 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6187892 | 0.92 | MAP2K1 (0.45) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6208327 | 0.92 | MAP2K1 (0.52) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6398520 | 0.91 | PIM1 (0.46) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6399813 | 0.90 | MAP2K1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6187354 | 0.90 | MAP2K1 (0.48) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6399775 | 0.89 | MAP2K1 (0.46) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL24758444 | 0.89 | MAP2K1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6186483 | 0.89 | MAP2K1 (0.47) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6208038 | 0.89 | PIM1 (0.45) | MAP2K1MAP2K2PIM1CAMK2BBRAF | |
| SCHEMBL6188396 | 0.89 | MAP2K1 (0.43) | MAP2K1MAP2K2PIM1CAMK2BBRAF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |