SCHEMBL21067895

SCHEMBL21067895

CC(C)n1nc(-c2ccc3ncccc3c2)c2c(N)ncnc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 19/20 1.00
▸ PIK3CD O00329 15/20 1.00
▸ ABL1 P00519 15/20 1.00
▸ PIK3CA P42336 15/20 1.00
▸ PIK3CB P42338 15/20 1.00
▸ PIK3CG P48736 15/20 1.00
▸ PRKDC P78527 15/20 1.00
▸ MTOR P42345 15/20 1.00
▸ EGFR P00533 14/20 1.00
▸ HCK P08631 14/20 1.00
▸ KDR P35968 14/20 1.00
▸ EPHB4 P54760 14/20 1.00
▸ PI4KB Q9UBF8 3/20 1.00
▸ BACE1 P56817 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29391405 0.86 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL14574867 0.86 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL3615741 0.85 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL14574639 0.85 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL29390634 0.85 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL3610356 0.83 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL14617304 0.82 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL18196381 0.81 SRC (0.80) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL17962818 0.80 SRC (0.74) SRCPIK3CDABL1PIK3CAPIK3CB
SCHEMBL2468132 0.80 SRC (1.00) SRCPIK3CDABL1PIK3CAPIK3CB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210254056-A1 IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS CAMP4 THERAPEUTICS CORPORATION 2021-08-19 — — US disclosed
US-20190192691-A1 REGULATED BIOCIRCUIT SYSTEMS OBSIDIAN THERAPEUTICS, INC. 2019-06-27 — — US disclosed
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