Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 19/20 | 1.00 |
| ▸ | PIK3CA | P42336 | 18/20 | 1.00 |
| ▸ | PIK3CB | P42338 | 18/20 | 1.00 |
| ▸ | PIK3CG | P48736 | 18/20 | 1.00 |
| ▸ | PRKDC | P78527 | 18/20 | 1.00 |
| ▸ | ABL1 | P00519 | 17/20 | 1.00 |
| ▸ | EGFR | P00533 | 17/20 | 1.00 |
| ▸ | HCK | P08631 | 17/20 | 1.00 |
| ▸ | SRC | P12931 | 17/20 | 1.00 |
| ▸ | KDR | P35968 | 17/20 | 1.00 |
| ▸ | MTOR | P42345 | 17/20 | 1.00 |
| ▸ | EPHB4 | P54760 | 17/20 | 1.00 |
| ▸ | PI4KB | Q9UBF8 | 13/20 | 1.00 |
| ▸ | ITK | Q08881 | 1/20 | 0.69 |
| ▸ | BTK | Q06187 | 1/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3603658 | 0.98 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL3616908 | 0.91 | EGFR (1.00) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL16655475 | 0.86 | PIK3CD (0.84) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL16655570 | 0.85 | PIK3CD (0.75) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL4827163 | 0.83 | SRC (0.83) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL12105019 | 0.83 | SRC (0.70) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL15087027 | 0.83 | SRC (0.72) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL4826071 | 0.83 | EGFR (0.81) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL23997152 | 0.81 | LCK (0.69) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC | |
| SCHEMBL16654231 | 0.81 | PIK3CD (0.67) | PIK3CDPIK3CAPIK3CBPIK3CGPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |