Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 8/20 | 0.61 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5442360 | 0.82 | GRIN2B (0.46) | MIFALDH1A1GRIN2BTSHRSLC6A4 | |
| SCHEMBL13664654 | 0.80 | MIF (0.60) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL13667977 | 0.79 | GRIN2B (0.49) | ALDH1A1GRIN2BTSHRMAPTSLC6A4 | |
| SCHEMBL1815294 | 0.79 | MIF (0.71) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2141861 | 0.78 | MIF (0.77) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL13452601 | 0.76 | GRIN2B (0.49) | ALDH1A1GRIN2BTSHRSLC6A4 | |
| SCHEMBL3849073 | 0.76 | MIF (0.68) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL354853 | 0.76 | MIF (1.00) | MIFTRPA1ALDH1A1CYP3A4HPGD | |
| SCHEMBL2092524 | 0.76 | GRIN2B (0.53) | ALDH1A1GRIN2BTSHRSLC6A4 | |
| SCHEMBL1020500 | 0.73 | P2RY6 (0.47) | MIFALDH1A1CYP3A4TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023163555-A1 | NOVEL HYDANTOIN DERIVATIVES AND USES THEREOF | (주)셀로스바이오텍 | 2023-08-31 | — | — | WO | disclosed |
| WO-2020021544-A1 | CANNABIDIOL AND METHYLTHIO-BUTYL-ISOTHIOCYANATE FOR TREATING INFLAMMATORY DISEASES | BOL PHARMA LTD. (IL) | 2020-01-30 | — | — | WO | disclosed |
| US-20120208879-A1 | METHODS AND PHARMACEUTICAL COMPOSITIONS USEFUL FOR TREATING PSORIASIS | GAVISH-GALILEE BIO APPLICATIONS LTD. (IL) | 2012-08-16 | — | — | US | disclosed |
| US-8158161-B2 | Methods and pharmaceutical compositions useful for treating psoriasis | S.U.L.V.E. LTD. (IL) | 2012-04-17 | — | — | US | disclosed |
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | SOCIETE DE CONSEILS DE RECHERCHES ET (FR) | 2009-10-29 | — | — | US | disclosed |
| US-20080044497-A1 | Methods and Pharmaceutical Compositions Useful for Treating Psoriasis | S.U.L.V.E. LTD. (IL) | 2008-02-21 | — | — | US | disclosed |
| EP-0354297-B1 | THIADIAZINES, PROCESS FOR PRODUCTION THEREOF, AND INSECTICIDAL AND ACARICIDAL AGENTS COMPRISING THE THIADIAZINES | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1992-08-05 | — | — | EP | disclosed |
| US-5021412-A | Protecting agricultural crops | MITSUI TOATSU CHEMICALS, INC. (JP) | 1991-06-04 | — | — | US | disclosed |
| EP-0354297-A1 | Thiadiazines, process for production thereof, and insecticidal and acaricidal agents comprising the thiadiazines | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1990-02-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090270372-A1 | NOVEL DERIVATIVES OF BENZIMIDAZOLE AND IMIDAZO-PYRIDINE AND THEIR USE AS MEDICAMENTS | MC4R, MC3R, MC1R | MIF 277/4885TRPA1 601/4885ALDH1A1 2349/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.