Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 4/20 | 0.81 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.76 |
| ▸ | KDR | P35968 | 4/20 | 0.76 |
| ▸ | KIT | P10721 | 3/20 | 0.76 |
| ▸ | DDR1 | Q08345 | 5/20 | 0.75 |
| ▸ | DDR2 | Q16832 | 5/20 | 0.75 |
| ▸ | EPHB2 | P29323 | 3/20 | 0.75 |
| ▸ | LCK | P06239 | 5/20 | 0.71 |
| ▸ | SRC | P12931 | 4/20 | 0.71 |
| ▸ | APEX1 | P27695 | 2/20 | 0.70 |
| ▸ | POLB | P06746 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.70 |
| ▸ | BRAF | P15056 | 6/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.67 |
| ▸ | TSHR | P16473 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.67 |
| ▸ | TEK | Q02763 | 1/20 | 0.65 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | ESYT2 | A0FGR8 | 2/20 | 0.64 |
| ▸ | NBAS | A2RRP1 | 2/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24532082 | 0.87 | DDR1 (0.71) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL29584779 | 0.86 | DDR2 (1.00) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL23752371 | 0.86 | DDR2 (1.00) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL13878810 | 0.86 | CSF1R (0.71) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL1655072 | 0.85 | ABL1 (0.81) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL22025101 | 0.84 | PIKFYVE (0.69) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL5029480 | 0.84 | ABL1 (0.73) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL2679147 | 0.83 | CSF1R (0.73) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL10077740 | 0.83 | CSF1R (0.73) | CSF1RMAPK14KDRKITDDR1 | |
| SCHEMBL7152016 | 0.83 | ABL1 (0.71) | CSF1RMAPK14KDRKITDDR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |