Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK10 | P53779 | 12/20 | 1.00 |
| ▸ | MAPK14 | Q16539 | 11/20 | 1.00 |
| ▸ | MAPK8 | P45983 | 10/20 | 1.00 |
| ▸ | PIP5K1C | O60331 | 2/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.55 |
| ▸ | GSK3B | P49841 | 4/20 | 0.54 |
| ▸ | BUB1 | O43683 | 2/20 | 0.54 |
| ▸ | PIP5K1B | O14986 | 1/20 | 0.53 |
| ▸ | PIP5K1A | Q99755 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 2/20 | 0.52 |
| ▸ | CDK2 | P24941 | 2/20 | 0.52 |
| ▸ | CDK9 | P50750 | 2/20 | 0.52 |
| ▸ | CDK3 | Q00526 | 2/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.52 |
| ▸ | GSK3A | P49840 | 1/20 | 0.52 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17223597 | 1.00 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518805 | 1.00 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518737 | 0.89 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518633 | 0.89 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518970 | 0.89 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518865 | 0.83 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL12656770 | 0.82 | MAPK14 (0.67) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518733 | 0.81 | MAPK10 (0.72) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL12656748 | 0.81 | MAPK14 (0.65) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA | |
| SCHEMBL1518834 | 0.80 | MAPK10 (1.00) | MAPK10MAPK14MAPK8PIP5K1CPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210254056-A1 | IDENTIFICATION AND TARGETED MODULATION OF GENE SIGNALING NETWORKS | CAMP4 THERAPEUTICS CORPORATION | 2021-08-19 | — | — | US | disclosed |
| US-20190192691-A1 | REGULATED BIOCIRCUIT SYSTEMS | OBSIDIAN THERAPEUTICS, INC. | 2019-06-27 | — | — | US | disclosed |